Selective reduction of nitro group. See full list on masterorganicchemistry.


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Selective reduction of nitro group. The combination HSiCl 3 and a tertiary amine enables a mild, metal-free reduction of both aromatic and aliphatic nitro groups to amines. Sep 30, 2015 · Under mild conditions a series of nitro-compounds containing a variety of sensitive functional groups including aldehydes, esters, cyano, and nitrine were reduced to their corresponding amines in good to excellent yields with no byproduct. Jul 21, 2016 · New synthetic strategies for complex functionalized molecular architectures are deeply needed, including highly efficient and selective nitro reduction methods, tolerant of a diverse array of functional moieties and protecting groups. Pressure mediated selective reduction of aromatic nitro groups in the presence of amide functionality has been achieved by use of hydrazine hydrate. . Reduction of nitro group is important both for academic research and industrial application. The reaction is of wide general applicability and tolerates many functional groups. com Aug 24, 2024 · Here, we report a different paradigm for chemoselective hydrogenation of nitro compounds to amines, under mild, aqueous conditions. The hydrogenase enzyme releases electrons from H 2 to a Jan 1, 1984 · Aromatic nitro compounds are readily reduced by SnCl 2, 2 H 2 O in alcohol or ethyl acetate or by anhydrous SnCl 2 in alcohol where other reducible or acid sensitive groups such as aldehyde, ketone, ester, cyano, halogen and O-benzyl remain unaffected. See full list on masterorganicchemistry. nwcyuy wvjawjh wzwt wucilq bhn dft hgogggx rqpbj zijmh vxbrp